Inter Miami took the lead in the 14th minute through Facundo Farias.
LAFC had a number of chances to equalize in the first half, but they were denied by good saves from Inter Miami goalkeeper Nick Marsman
The best chance fell to Denis Bouanga, who fired wide from close range in the 38th minute
Inter Miami doubled their lead in the 57th minute through a Lionel Messi assist.
The Argentine superstar played a brilliant pass through to Jordi Alba, who slotted the ball past Crepeau.
Messi got his second assist of the night in the 72nd minute.
LAFC pulled a goal back in the 90th minute through Carlos Vela.
Inter Miami doubled their lead in the 57th minute through a Lionel Messi assist.